PyroHMMvar: a sensitive and accurate method to call short INDELs and SNPs for Ion Torrent and 454 data

Motivation: The identification of short indels and SNPs from Ion Torrent and 454 reads is a challenging problem, essentially because these techniques are prone to sequence erroneously at homopolymers and can, therefore, raise indels in reads. Most of the existing mapping programs do not model homopo[……]

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