STAMP (Statistical Analysis of Metagenomic Profiles)

STAMP

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Using STAMP to identify SEED subsystems which are differentially abundant between CandidatusAccumulibacter phosphatis sequences obtained from a pair of enhanced biological phosphorus removal (EBPR) sludge metagenomes(data originally described in Parks and Beiko, 2010).

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Reading the NCBI’s GEO microarray SOFT files in R/BioConductor

http://www2.warwick.ac.uk/fac/sci/moac/people/students/peter_cock/r/geo/ This page discusses how to load GEO SOFT format microarray data from the Gene Expression Omnibus database (GEO) (hosted by the NCBI) into R/BioConductor. SOFT stands for Simple Omnibus Format in Text. There are actually four[……]

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Meta分析(Meta-analysis)简介

Meta分析的由来: Meta分析(Meta-analysis)是心理学家Glass于1976年首次提出,原文是这样的: Meta-analysis refers to the analysis of analyses. I use it to refer to the statistical analysis of a large collection of results from individual studies for the purpose of integrating the findings. It connotes a rigorous alternative to t[……]

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真理在缩水,还是上帝在掷骰子?(转贴)

最近在Google Reader中看见科学松鼠会有两篇文章被频繁分享,名为《真理在缩水——现代科学研究方法并不尽善尽美?》()与(),下文简称《缩水》。文章很有意思,而实际上说的是我们的老本行——统计学,因此我在这里也发表一些我的想法和理解,包括这两年我在美帝学习的一些思考,部分内容受益于两位老师Kaiser和Nettleton教授,先向他们致谢(尽管他们永远都不会看到这篇文章)。同时我也要先说明一下,读这篇文章可能会很花时间(至少我花了大约二十小时写这篇文章),即使我的观点没有价值,我相信里面的引用文献是有价值的。 初读文章,我脑子里冒出的一句话是“上帝在跟我们掷骰子”,文中给出了[……]

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