LOCAS, a new NGS assembler particularly designed for low coverage assembly of eukaryotic genome

Next Generation Sequencing (NGS) is a frequently applied approach to detect sequence variationsbetween highly related genomes. Recent large-scale re-sequencing studies as the Human 1000 GenomesProject utilize NGS data of low coverage to afford sequencing of hundreds of individuals. Here, SNPsand micro-indels can be detected by applying an alignment-consensus approach. However,computational methods capable of […]

ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data

Description

ANNOVA is an efficient software tool to utilize update-to-date information to functionally annotategenetic variants detected from diverse genomes. Given a list of variants with chromosome, startposition, end position and observed nucleotides, ANNOVAR can identify whether SNPs or indels causeprotein coding changes and what is the amino acids that were changed, or identify variants […]

ubuntu 9.10 下安装glimmer3失败及其解决办法

(1)安装前,先修改src/Common下第26行#include <string> 为 #include <cstring>;再make,可是仍然会产生以下错误 * Make Target is all ##### Making Directory /usr/local/glimmer3.02/src/Common all ##### make[1]: 正在进入目录 `/usr/local/glimmer3.02/src/Common’ @@@@@@@@@@@@@@@@@@@ delcher.cc @@@@@@@@@@@@@@@@@@@@@ @@@@@@@@@@@@@@@@@@@ fasta.cc @@@@@@@@@@@@@@@@@@@@@ @@@@@@@@@@@@@@@@@@@ gene.cc @@@@@@@@@@@@@@@@@@@@@ gene.cc: In member function ‘void PWM_t::Print(FILE*)’: gene.cc:263: warning: deprecated conversion from string constant to ‘char*’ gene.cc: In function ‘int Char_Sub(char)’: gene.cc:448: error: invalid conversion from ‘const char*’ […]